In API manufacturing, contrary to the traditional use of multiple utilities, single fluid heat transfer systems are advantageous. These systems can be designed even for specific applications, and engineered and built at site.
Active Pharmaceutical Ingredient (API) manufacturing involves batch reaction, work-up, layer separation, filtration, distillation and drying. Again, batch reaction involves heating and cooling stages ranging from -20 to +150°C. Conventionally, this was being done with multiple utilities such as chilled brine, chilled water, cooling water, hot water & low pressure steam.
Single fluid heat transfer system is normally connected to the Single/Multiple reactors – where the temperature of the system is varied as per the process requirement, thus maintaining the constant temperature difference between the process and fluid temperature – this gives precise control over heating and cooling rate. Thus, not only the temperature is controlled as a critical process parameter but also the heating-and-cooling time is controlled as a critical parameter – this results in batch to batch consistency and higher yield.
Bionic Technologies is having expertise in manufacturing of various types and capacity of heating and cooling systems. We are engaged in providing Heating & Cooling Solutions that is widely demanded in process(Crystallization & Non aqueous reactions) & utility(AHU’d) applications
Bionic Technologies is Provide the single fluid heat transfer system is the skid mounted system with PLC-based control/Relay based control. The system can also be designed for specific applications, engineered and built at site using various components of the system – such as heat exchangers, pumps, sensors, instrumentation and wiring. Multi temperature single fluid systems are also used to cater to various reactors – when the facility has more than one reactor operating at single temperature range.
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